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Page 1
Choline acetyltransferase-expressing T cells are required to control chronic viral infection.
Cox MA, Duncan GS, Lin GHY, Steinberg BE, Yu LX, Brenner D, Buckler LN, Elia AJ, Wakeham AC, Nieman B, Dominguez-Brauer C, Elford AR, Gill KT, Kubli SP, Haight J, Berger T, Ohashi PS, Tracey KJ, Olofsson PS, Mak TW. Cox MA, et al. Among authors: wakeham ac. Science. 2019 Feb 8;363(6427):639-644. doi: 10.1126/science.aau9072. Science. 2019. PMID: 30733420 Free PMC article.
Tumor-specific cholinergic CD4+ T lymphocytes guide immunosurveillance of hepatocellular carcinoma.
Zheng C, Snow BE, Elia AJ, Nechanitzky R, Dominguez-Brauer C, Liu S, Tong Y, Cox MA, Focaccia E, Wakeham AC, Haight J, Tobin C, Hodgson K, Gill KT, Ma W, Berger T, Heikenwälder M, Saunders ME, Fortin J, Leung SY, Mak TW. Zheng C, et al. Among authors: wakeham ac. Nat Cancer. 2023 Oct;4(10):1437-1454. doi: 10.1038/s43018-023-00624-w. Epub 2023 Aug 28. Nat Cancer. 2023. PMID: 37640929 Free PMC article.
Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis.
Nechanitzky R, Nechanitzky D, Ramachandran P, Duncan GS, Zheng C, Göbl C, Gill KT, Haight J, Wakeham AC, Snow BE, Bradaschia-Correa V, Ganguly M, Lu Z, Saunders ME, Flavell RA, Mak TW. Nechanitzky R, et al. Among authors: wakeham ac. Cell Death Differ. 2023 Feb;30(2):407-416. doi: 10.1038/s41418-022-01092-y. Epub 2022 Dec 17. Cell Death Differ. 2023. PMID: 36528755 Free PMC article.
Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs.
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski KV, Alicea-Torres K, Li J, Todd L, Zhang H, Beiting DP, Sander C, Kirkwood JM, Snow BE, Wakeham AC, Mak TW, Diehl JA, Koumenis C, Ryeom SW, Stanger BZ, Puré E, Gabrilovich DI, Fuchs SY. Gui J, et al. Among authors: wakeham ac. Nat Cancer. 2020 Jun;1(6):603-619. doi: 10.1038/s43018-020-0064-0. Epub 2020 May 25. Nat Cancer. 2020. PMID: 34124690 Free PMC article.
CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression.
Nechanitzky R, Ramachandran P, Nechanitzky D, Li WY, Wakeham AC, Haight J, Saunders ME, Epelman S, Mak TW. Nechanitzky R, et al. Among authors: wakeham ac. Cell Death Differ. 2024 Mar;31(3):265-279. doi: 10.1038/s41418-024-01268-8. Epub 2024 Feb 21. Cell Death Differ. 2024. PMID: 38383888 Free PMC article.